For research use only. Not for therapeutic Use.
BCL6-IN-4（Cat No.:I044491）is a potent small-molecule inhibitor targeting B-cell lymphoma 6 (BCL6), a transcriptional repressor implicated in various cancers, particularly diffuse large B-cell lymphoma (DLBCL). By disrupting the interaction between BCL6 and its corepressor complexes, BCL6-IN-4 reactivates suppressed tumor suppressor genes, promoting apoptosis and halting cancer cell proliferation. This compound is valuable in preclinical studies exploring epigenetic modulation and transcriptional regulation in oncogenesis. Its selectivity and efficacy make it a promising lead for therapeutic development and a useful tool in cancer biology research focused on BCL6-driven malignancies.
| CAS Number | 2253879-65-9 |
| Synonyms | 5-[[5-chloro-2-(2,2,6,6-tetramethylmorpholin-4-yl)pyrimidin-4-yl]amino]-3-(3-hydroxy-3-methylbutyl)-1-methylbenzimidazol-2-one |
| Molecular Formula | C25H35ClN6O3 |
| Purity | ≥95% |
| IUPAC Name | 5-[[5-chloro-2-(2,2,6,6-tetramethylmorpholin-4-yl)pyrimidin-4-yl]amino]-3-(3-hydroxy-3-methylbutyl)-1-methylbenzimidazol-2-one |
| InChI | InChI=1S/C25H35ClN6O3/c1-23(2,34)10-11-32-19-12-16(8-9-18(19)30(7)22(32)33)28-20-17(26)13-27-21(29-20)31-14-24(3,4)35-25(5,6)15-31/h8-9,12-13,34H,10-11,14-15H2,1-7H3,(H,27,28,29) |
| InChIKey | BGCPLWWYPZAURQ-UHFFFAOYSA-N |
| SMILES | CC1(CN(CC(O1)(C)C)C2=NC=C(C(=N2)NC3=CC4=C(C=C3)N(C(=O)N4CCC(C)(C)O)C)Cl)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
