For research use only. Not for therapeutic Use.
BCI (Cat No.:I017887) is a small-molecule inhibitor that selectively targets dual-specificity phosphatases DUSP1 and DUSP6 (MKP-1/6), which are negative regulators of ERK1/2 MAPK signaling. By blocking DUSP activity, BCI sustains ERK activation, influencing cell proliferation, differentiation, and survival. It has been widely used in developmental biology, cancer research, and regenerative studies to probe MAPK pathway regulation. BCI is particularly valuable for understanding phosphatase-controlled feedback mechanisms in signal transduction and supports exploration of therapeutic strategies involving ERK/MAPK modulation in disease contexts.
| CAS Number | 1245792-51-1 |
| Molecular Formula | C22H23NO |
| Purity | ≥95% |
| IUPAC Name | (2E)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one |
| InChI | InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15+ |
| InChIKey | XJDKPLZUXCIMIS-HMMYKYKNSA-N |
| SMILES | C1CCC(CC1)NC\2C3=CC=CC=C3C(=O)/C2=C/C4=CC=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
