For research use only. Not for therapeutic Use.
BC-1382(Cat No.:I023046)is a potent, selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε), enzymes implicated in circadian rhythm regulation, neurodegeneration, and certain cancers. Designed to cross the blood-brain barrier, BC-1382 exhibits strong in vitro and in vivo efficacy, modulating key signaling pathways linked to tau phosphorylation and sleep-wake cycles. Its high specificity reduces off-target effects, making it a valuable research tool in chronobiology and neurodegenerative disease studies. BC-1382 supports exploration of CK1δ/ε as therapeutic targets in Alzheimer’s disease, mood disorders, and other central nervous system conditions.
| CAS Number | 1013753-99-5 |
| Synonyms | 1-(benzenesulfonyl)-N-[(2S)-1-[(2-methoxyphenyl)methylamino]-1-oxopropan-2-yl]piperidine-4-carboxamide |
| Molecular Formula | C23H29N3O5S |
| Purity | ≥95% |
| IUPAC Name | 1-(benzenesulfonyl)-N-[(2S)-1-[(2-methoxyphenyl)methylamino]-1-oxopropan-2-yl]piperidine-4-carboxamide |
| InChI | InChI=1S/C23H29N3O5S/c1-17(22(27)24-16-19-8-6-7-11-21(19)31-2)25-23(28)18-12-14-26(15-13-18)32(29,30)20-9-4-3-5-10-20/h3-11,17-18H,12-16H2,1-2H3,(H,24,27)(H,25,28)/t17-/m0/s1 |
| InChIKey | RCWXKFCEGKXUIN-KRWDZBQOSA-N |
| SMILES | C[C@@H](C(=O)NCC1=CC=CC=C1OC)NC(=O)C2CCN(CC2)S(=O)(=O)C3=CC=CC=C3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |