For research use only. Not for therapeutic Use.
BBIQ(CAT: I016680) is an imidazoquinoline-based compound and a potent, selective agonist of Toll-like receptor 7 (TLR7), exhibiting an EC₅₀ of 59.1 nM for human TLR7. By activating innate immune pathways, BBIQ stimulates cytokine release and enhances antigen-presenting cell activity, making it a powerful immunomodulator. It is widely explored as a vaccine adjuvant, where it boosts adaptive immune responses and improves vaccine efficacy. Beyond vaccinology, BBIQ is also studied in cancer immunotherapy and infectious disease models as a tool to probe TLR7-mediated signaling. Its high potency and selectivity provide researchers with a reliable reagent for advancing immunology and translational medicine.
| CAS Number | 1229024-57-0 |
| Synonyms | 1-benzyl-2-butylimidazo[4,5-c]quinolin-4-amine |
| Molecular Formula | C21H22N4 |
| Purity | ≥95% |
| IUPAC Name | 1-benzyl-2-butylimidazo[4,5-c]quinolin-4-amine |
| InChI | InChI=1S/C21H22N4/c1-2-3-13-18-24-19-20(25(18)14-15-9-5-4-6-10-15)16-11-7-8-12-17(16)23-21(19)22/h4-12H,2-3,13-14H2,1H3,(H2,22,23) |
| InChIKey | CQBDMXYZNLJUFT-UHFFFAOYSA-N |
| SMILES | CCCCC1=NC2=C(N1CC3=CC=CC=C3)C4=CC=CC=C4N=C2N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
