BAY-2402234 - CAS 2225819-06-5
BAY-2402234 (CAT: I019879) is a selective inhibitor of dihydroorotate dehydrogenase (DHODH) developed for the treatment of myeloid malignancies. DHODH is a crucial enzyme involved in the de novo pyrimidine synthesis pathway. By inhibiting DHODH, BAY-2402234 disrupts the production of pyrimidine nucleotides, essential building blocks for DNA and RNA synthesis. This targeted inhibition of DHODH holds therapeutic potential in the treatment of myeloid malignancies, such as certain forms of leukemia.
* For research use only. Not for human or veterinary use.