BAY 1135626

• CAT Number: I043403
• CAS Number: 1404071-37-9
• Molecular Formula: C55H86N10O11
• Molecular Weight: 1063.33
• Purity: ≥95%
• Synonyms: (2S)-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-2-[[(2S)-2-[[4-[2-[6-(2,5-dioxopyrrol-1-yl)hexanoyl]hydrazinyl]-4-oxobutyl]-methylamino]-3-methylbutanoyl]amino]-N,3-dimethylbutanamide
• InChI: InChI=1S/C55H86N10O11/c1-12-35(6)50(42(75-10)31-47(70)64-29-18-22-41(64)51(76-11)36(7)53(72)58-40(52(56)71)30-37-32-57-39-21-16-15-20-38(37)39)63(9)55(74)48(33(2)3)59-54(73)49(34(4)5)62(8)27-19-24-44(67)61-60-43(66)23-14-13-17-28-65-45(68)25-26-46(65)69/h15-16,20-21,25-26,32-36,40-42,48-51,57H,12-14,17-19,22-24,27-31H2,1-11H3,(H2,56,71)(H,58,72)(H,59,73)(H,60,66)(H,61,67)/t35-,36+,40-,41-,42+,48-,49-,50-,51+/m0/s1
• InChIKey: WKLHCCJTASJGSQ-LYBNSWTHSA-N
• SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)CCCC(=O)NNC(=O)CCCCCN4C(=O)C=CC4=O

BAY 1135626（Cat No.:I043403）is an investigational small molecule being studied for its potential in treating various cancers. It is a selective inhibitor of the fibroblast growth factor receptor (FGFR) 1-3, which plays a critical role in tumor growth, angiogenesis, and metastasis. By targeting FGFR signaling, BAY 1135626 may help to block cancer cell proliferation and tumor progression. Ongoing clinical trials are focused on evaluating its efficacy, safety, and potential in cancers with FGFR mutations or alterations, offering a promising therapeutic option for patients with resistant or advanced malignancies.