Batifiban TFA

• CAT Number: I040338
• Molecular Formula: C37H52F3N11O11S2
• Molecular Weight: 948.21
• Purity: ≥95%
• IUPAC Name: 2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[3-(diaminomethylideneamino)propyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid;methane;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C34H47N11O9S2.C2HF3O2.CH4/c35-29(50)24-17-56-55-12-9-26(46)41-21(7-3-10-38-34(36)37)30(51)40-16-27(47)42-22(14-28(48)49)31(52)43-23(13-18-15-39-20-6-2-1-5-19(18)20)33(54)45-11-4-8-25(45)32(53)44-24;3-2(4,5)1(6)7;/h1-2,5-6,15,21-25,39H,3-4,7-14,16-17H2,(H2,35,50)(H,40,51)(H,41,46)(H,42,47)(H,43,52)(H,44,53)(H,48,49)(H4,36,37,38);(H,6,7);1H4/t21-,22-,23-,24-,25-;;/m0../s1
• InChIKey: BTHPDQICLCCWAG-NGRWTEOBSA-N
• SMILES: C.C1C[C@H]2C(=O)N[C@@H](CSSCCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCN=C(N)N)C(=O)N.C(=O)(C(F)(F)F)O

Batifiban TFA(CAT: I040338) is a potent, cyclic heptapeptide inhibitor of the glycoprotein IIb/IIIa (αIIbβ3) integrin receptor, which plays a central role in platelet aggregation. By mimicking the RGD sequence, it prevents fibrinogen and other ligands from binding to activated platelets, thereby reducing thrombus formation. The molecule contains a disulfide-bridged ring that enhances its receptor binding affinity and metabolic stability. As the trifluoroacetate (TFA) salt, Batifiban is highly water-soluble and suitable for both in vitro and in vivo studies. It is widely used in cardiovascular research, especially in evaluating anti-thrombotic therapies and integrin-related signaling in vascular and platelet biology.