Baloxavir-d4

• CAT Number: I040346
• CAS Number: 2415027-80-2
• Molecular Formula: C24H15D4F2N3O4S
• Molecular Weight: 487.51
• Purity: ≥95%
• Synonyms: (3R)-6,6,7,7-tetradeuterio-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-11-hydroxy-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-9,12-dione
• InChI: InChI=1S/C24H19F2N3O4S/c25-16-6-5-13-15(20(16)26)12-34-18-4-2-1-3-14(18)21(13)29-19-11-33-10-9-27(19)24(32)22-23(31)17(30)7-8-28(22)29/h1-8,19,21,31H,9-12H2/t19-,21+/m1/s1/i9D2,10D2
• InChIKey: FIDLLEYNNRGVFR-KZRIHOBTSA-N
• SMILES: [2H]C1(C(OC[C@@H]2N1C(=O)C3=C(C(=O)C=CN3N2[C@H]4C5=C(CSC6=CC=CC=C46)C(=C(C=C5)F)F)O)([2H])[2H])[2H]

Baloxavir-d4(CAT: I040346) is a deuterium-labeled analog of Baloxavir, designed for use in pharmacokinetic studies, drug metabolism investigations, and bioanalytical research. As an isotope-labeled antiviral reference compound, Baloxavir-d4 facilitates the precise quantification of Baloxavir in biological matrices via LC-MS/MS methods. It retains the core structure and activity profile of Baloxavir while incorporating four deuterium atoms for enhanced stability and differentiation in mass spectrometry assays. This compound is particularly valuable for tracking drug distribution, metabolic pathways, and interaction profiling in preclinical and clinical studies focused on influenza virus replication inhibition through cap-dependent endonuclease targeting.