Bacterial Sortase Substrate III, Abz/DNP TFA

• CAT Number: I046138
• Molecular Formula: C41H57N11O14.xC2HF3O2
• Purity: ≥95%
• IUPAC Name: (4S)-4-[[(2S)-1-[(2S)-2-[(2-aminobenzoyl)amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-5-[[(2S,3R)-1-[[2-[[(2S)-1-amino-6-(2,4-dinitroanilino)-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C41H57N11O14.C2HF3O2/c1-22(2)19-30(48-37(58)25-9-4-5-10-26(25)42)41(62)50-18-8-12-31(50)39(60)47-29(15-16-34(55)56)38(59)49-35(23(3)53)40(61)45-21-33(54)46-28(36(43)57)11-6-7-17-44-27-14-13-24(51(63)64)20-32(27)52(65)66;3-2(4,5)1(6)7/h4-5,9-10,13-14,20,22-23,28-31,35,44,53H,6-8,11-12,15-19,21,42H2,1-3H3,(H2,43,57)(H,45,61)(H,46,54)(H,47,60)(H,48,58)(H,49,59)(H,55,56);(H,6,7)/t23-,28+,29+,30+,31+,35+;/m1./s1
• InChIKey: ZWHRNQBMVAKJAX-XKERDFBISA-N
• SMILES: C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CCCCNC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-])C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)C3=CC=CC=C3N)O.C(=O)(C(F)(F)F)O

Bacterial Sortase Substrate III, Abz/DNP TFA（Cat No.:I046138）is a fluorogenic peptide substrate designed for monitoring sortase A enzymatic activity. It contains an Abz (2-aminobenzoyl) fluorescent donor and a DNP (dinitrophenyl) quencher, enabling sensitive detection of cleavage events. Sortase A, a bacterial transpeptidase, catalyzes protein anchoring to cell walls and is a target in antimicrobial research. The TFA salt form enhances solubility and handling in laboratory assays. This substrate is widely used in enzymology, microbiology, and drug discovery, providing a robust tool for screening inhibitors and studying bacterial pathogenesis mechanisms.