Bactenecin TFA

• CAT Number: I045856
• Molecular Formula: C65H119F3N24O15S2
• Molecular Weight: 1597.94
• Purity: ≥95%
• IUPAC Name: (2S)-2-[[(4R,7S,10S,13S,16S,19S,22S,25S,28R)-28-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-13,22-bis[(2S)-butan-2-yl]-10,25-bis[3-(diaminomethylideneamino)propyl]-6,9,12,15,18,21,24,27-octaoxo-7,16,19-tri(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26-octazacyclononacosane-4-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C63H118N24O13S2.C2HF3O2/c1-13-34(11)46-57(97)78-38(21-17-25-75-62(69)70)49(89)83-43(31(5)6)54(94)82-42(53(93)79-39(59(99)100)22-18-26-76-63(71)72)29-102-101-28-41(81-51(91)40(27-30(3)4)80-48(88)36(64)19-15-23-73-60(65)66)52(92)77-37(20-16-24-74-61(67)68)50(90)86-47(35(12)14-2)58(98)85-44(32(7)8)55(95)84-45(33(9)10)56(96)87-46;3-2(4,5)1(6)7/h30-47H,13-29,64H2,1-12H3,(H,77,92)(H,78,97)(H,79,93)(H,80,88)(H,81,91)(H,82,94)(H,83,89)(H,84,95)(H,85,98)(H,86,90)(H,87,96)(H,99,100)(H4,65,66,73)(H4,67,68,74)(H4,69,70,75)(H4,71,72,76);(H,6,7)/t34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-;/m0./s1
• InChIKey: POTROQMLBPXNBU-FDKPIWNJSA-N
• SMILES: CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)C(C)C)CCCN=C(N)N)[C@@H](C)CC)C(C)C)C(C)C.C(=O)(C(F)(F)F)O

Bactenecin TFA（Cat No.:I045856）is a cationic antimicrobial peptide originally isolated from bovine neutrophils, belonging to the cathelicidin family. It exhibits strong activity against Gram-positive and Gram-negative bacteria by disrupting microbial membranes, contributing to innate host defense. As the trifluoroacetate (TFA) salt, it provides enhanced stability and solubility for laboratory use. Bactenecin is widely studied in infection biology, immunology, and peptide-based drug development due to its broad-spectrum antimicrobial potential and low toxicity. It serves as a valuable model for designing novel therapeutic peptides targeting resistant pathogens.