For research use only. Not for therapeutic Use.
BA 1 TFA(Cat No.:I045795)is a synthetic peptide agonist of the formyl peptide receptor 2 (FPR2/ALX), a G protein–coupled receptor involved in immune regulation and resolution of inflammation. By activating FPR2, BA 1 promotes anti-inflammatory signaling, enhances phagocytosis, and supports tissue repair processes. Supplied as a trifluoroacetate (TFA) salt, it offers improved solubility and stability for laboratory use. BA 1 TFA is widely applied in immunology and inflammation research to investigate pro-resolving pathways, innate immune responses, and therapeutic strategies for chronic inflammatory and autoimmune diseases.
Molecular Formula | C59H77F3N14O13 |
Purity | ≥95% |
IUPAC Name | (2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide |
InChI | InChI=1S/C57H76N14O11/c1-6-7-16-42(49(60)74)66-55(80)44(25-34-13-9-8-10-14-34)69-56(81)46(27-37-29-61-30-63-37)68-50(75)32(4)65-57(82)48(31(2)3)71-51(76)33(5)64-54(79)45(26-36-28-62-41-17-12-11-15-39(36)41)70-53(78)43(22-23-47(59)73)67-52(77)40(58)24-35-18-20-38(72)21-19-35/h8-15,17-21,28-33,40,42-46,48,62,72H,6-7,16,22-27,58H2,1-5H3,(H2,59,73)(H2,60,74)(H,61,63)(H,64,79)(H,65,82)(H,66,80)(H,67,77)(H,68,75)(H,69,81)(H,70,78)(H,71,76)/t32-,33-,40+,42-,43-,44-,45-,46-,48-/m0/s1 |
InChIKey | BXSSCSKCOFKPOK-ZWAOGYCRSA-N |
SMILES | CCCC[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](CC5=CC=C(C=C5)O)N |
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