Azilsartan mepixetil

For research use only. Not for therapeutic Use.

  • CAT Number: I045120
  • CAS Number: 1596357-16-2
  • Molecular Formula: C36H34N6O8
  • Molecular Weight: 678.69
  • Purity: ≥95%
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Azilsartan medoxomil (Cat No.:I045120) is a prodrug of azilsartan, an angiotensin II receptor blocker (ARB) used primarily for the treatment of hypertension. Once activated in the body, it selectively blocks the AT1 receptor, preventing angiotensin II from inducing vasoconstriction, aldosterone secretion, and sympathetic activation—thereby reducing blood pressure and cardiovascular strain. Azilsartan mepixetil demonstrates high potency, prolonged receptor binding, and effective 24-hour blood pressure control. It is often studied for its potential benefits in heart failure, kidney protection, and metabolic syndrome. Supplied for cardiovascular and antihypertensive research.


CAS Number 1596357-16-2
Synonyms

1-[(3,5,6-trimethylpyrazin-2-yl)methoxycarbonyloxy]ethyl 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

Molecular Formula C36H34N6O8
Purity ≥95%
IUPAC Name 1-[(3,5,6-trimethylpyrazin-2-yl)methoxycarbonyloxy]ethyl 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
InChI InChI=1S/C36H34N6O8/c1-6-46-34-39-29-13-9-12-28(33(43)48-23(5)49-36(45)47-19-30-22(4)37-20(2)21(3)38-30)31(29)42(34)18-24-14-16-25(17-15-24)26-10-7-8-11-27(26)32-40-35(44)50-41-32/h7-17,23H,6,18-19H2,1-5H3,(H,40,41,44)
InChIKey JXSDNNVNQNYJSP-UHFFFAOYSA-N
SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)OC(C)OC(=O)OCC6=NC(=C(N=C6C)C)C
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