Azido-PEG8-PFP ester

• CAT Number: I015822
• CAS Number: 2055014-62-3
• Molecular Formula: C25H36F5N3O10
• Molecular Weight: 633.56
• Purity: ≥95%
• Synonyms: (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C25H36F5N3O10/c26-20-21(27)23(29)25(24(30)22(20)28)43-19(34)1-3-35-5-7-37-9-11-39-13-15-41-17-18-42-16-14-40-12-10-38-8-6-36-4-2-32-33-31/h1-18H2
• InChIKey: FLLXHBTXSPGUHL-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F

Azido-PEG8-PFP ester（Cat No.:I015822）is a heterobifunctional polyethylene glycol linker designed for efficient and versatile bioconjugation. It carries a terminal azide group for copper-catalyzed or strain-promoted click chemistry with alkynes, and a reactive pentafluorophenyl (PFP) ester that couples selectively with primary amines to form stable amide bonds. The PEG8 spacer imparts hydrophilicity, flexibility, and reduced steric hindrance, ensuring excellent solubility and biomolecular accessibility in diverse environments. This reagent is widely applied in proteomics, chemical biology, drug discovery, and biomaterials, enabling modular assembly, surface functionalization, and multifunctional probe development with high precision.