Azido-PEG6-MS

• CAT Number: I044639
• CAS Number: 352439-38-4
• Molecular Formula: C13H27N3O8S
• Molecular Weight: 385.43
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate
• InChI: InChI=1S/C13H27N3O8S/c1-25(17,18)24-13-12-23-11-10-22-9-8-21-7-6-20-5-4-19-3-2-15-16-14/h2-13H2,1H3
• InChIKey: VSSFOIKXGWLEBU-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)OCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG6-MS（Cat No.:I044639）is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group and a methanesulfonate (mesylate, MS) group, connected by a six-unit PEG chain. The azide moiety enables bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the mesylate group serves as an excellent leaving group for nucleophilic substitution with amines, thiols, or other nucleophiles. The PEG6 spacer imparts hydrophilicity, flexibility, and reduces steric hindrance. This reagent is widely used in bioconjugation, drug delivery system design, and the functionalization of biomolecules or surfaces for advanced biomedical and chemical biology applications.