For research use only. Not for therapeutic Use.
Azido-PEG3-SSPy（Cat No.:I045945）is a cleavable, heterobifunctional linker designed for bioorthogonal conjugation and controlled release. It features an azide group compatible with copper-catalyzed or strain-promoted click chemistry with alkynes, enabling highly selective and efficient labeling. The PEG3 spacer enhances aqueous solubility, flexibility, and minimizes steric hindrance in biomolecular systems. The pyridyl disulfide (SSPy) moiety reacts with free thiols to form stable disulfide linkages, which are cleavable under reducing conditions for reversible conjugation. This reagent is particularly useful in chemical biology, drug delivery, proteomics, and targeted therapeutic research.
| CAS Number | 2749281-80-7 |
| Synonyms | 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyldisulfanyl]pyridine |
| Molecular Formula | C13H20N4O3S2 |
| Purity | ≥95% |
| IUPAC Name | 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyldisulfanyl]pyridine |
| InChI | InChI=1S/C13H20N4O3S2/c14-17-16-5-6-18-7-8-19-9-10-20-11-12-21-22-13-3-1-2-4-15-13/h1-4H,5-12H2 |
| InChIKey | SKOJGYNLNMOKDO-UHFFFAOYSA-N |
| SMILES | C1=CC=NC(=C1)SSCCOCCOCCOCCN=[N+]=[N-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
