Azido-PEG3-azide

• CAT Number: M008921
• CAS Number: 101187-39-7
• Molecular Formula: C8H16N6O3
• Molecular Weight: 244.25
• Purity: ≥95%
• Synonyms: 1-azido-2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethane
• InChI: InChI=1S/C8H16N6O3/c9-13-11-1-3-15-5-7-17-8-6-16-4-2-12-14-10/h1-8H2
• InChIKey: SFMMXKLNFMIUCH-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCN=[N+]=[N-])N=[N+]=[N-]

Azido-PEG3-azide(CAT: M008921) is a bifunctional polyethylene glycol (PEG) linker terminated with azide groups on both ends of a three-unit PEG chain. The dual azide functionalities make it highly reactive in bioorthogonal click chemistry, particularly copper-catalyzed (CuAAC) or strain-promoted azide–alkyne cycloaddition (SPAAC), enabling efficient conjugation with alkyne-modified molecules. The PEG3 spacer provides moderate flexibility and hydrophilicity, improving solubility and reducing steric hindrance while maintaining compact molecular design. This versatile reagent is commonly used in bioconjugation, surface modification, polymer chemistry, and materials science where short, reactive PEG linkers are required for controlled molecular assembly and functionalization.