Azido-PEG12-NHS ester

• CAT Number: I015834
• CAS Number: 2363756-50-5
• Molecular Formula: C31H56N4O16
• Molecular Weight: 740.79
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C31H56N4O16/c32-34-33-4-6-40-8-10-42-12-14-44-16-18-46-20-22-48-24-26-50-28-27-49-25-23-47-21-19-45-17-15-43-13-11-41-9-7-39-5-3-31(38)51-35-29(36)1-2-30(35)37/h1-28H2
• InChIKey: JSNJRDFOCXNHTB-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG12-NHS ester（Cat No.:I015834）is a heterobifunctional crosslinker featuring an azide group for copper-free or copper-catalyzed click chemistry and an NHS ester for efficient amine coupling. The PEG12 spacer provides an optimal balance between hydrophilicity and flexibility, improving solubility and minimizing steric hindrance while maintaining sufficient distance between functional groups. This reagent is ideal for bioconjugation, protein labeling, and the development of drug delivery systems where controlled spacing is critical. Its versatility makes it a valuable tool in chemical biology, diagnostics, and therapeutic research applications requiring stable, site-specific linkages.