Azido-PEG1-NHS ester

• CAT Number: I015836
• CAS Number: 1807530-06-8
• Molecular Formula: C9H12N4O5
• Molecular Weight: 256.22
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-(2-azidoethoxy)propanoate
• InChI: InChI=1S/C9H12N4O5/c10-12-11-4-6-17-5-3-9(16)18-13-7(14)1-2-8(13)15/h1-6H2
• InChIKey: MGKGKSFTIINDPY-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCN=[N+]=[N-]

Azido-PEG1-NHS ester（Cat No.:I015836）is a compact heterobifunctional crosslinker designed for efficient and site-specific bioconjugation. It carries an azide group compatible with copper-catalyzed or strain-promoted click chemistry and an NHS ester that reacts selectively with primary amines on proteins, peptides, and other biomolecules. The short PEG1 spacer introduces minimal distance between functional groups while improving solubility and reducing steric hindrance compared to non-PEG linkers. This reagent is especially suited for protein labeling, drug delivery, and probe development where a short, stable, and precise linkage is required for optimal performance.