Azide-PEG5-Tos

• CAT Number: I016024
• CAS Number: 236754-49-7
• Molecular Formula: C17H27N3O7S
• Molecular Weight: 417.48
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
• InChI: InChI=1S/C17H27N3O7S/c1-16-2-4-17(5-3-16)28(21,22)27-15-14-26-13-12-25-11-10-24-9-8-23-7-6-19-20-18/h2-5H,6-15H2,1H3
• InChIKey: RCRFPWKHJGMATE-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOCCN=[N+]=[N-]

Azide-PEG5-Tos（Cat No.:I016024）is a heterobifunctional polyethylene glycol linker containing an azide group on one terminus and a tosyl (tosylate) leaving group on the other. The azide moiety enables click chemistry reactions with alkynes, supporting efficient bioconjugation, labeling, and probe development. The tosyl functionality allows substitution by nucleophiles such as amines, alcohols, and thiols, facilitating further derivatization. The PEG5 spacer enhances hydrophilicity, increases molecular flexibility, and reduces steric hindrance, improving reaction efficiency. This reagent is widely applied in chemical biology, pharmaceutical research, and material science for modular conjugation strategies.