Azide-PEG3-Desthiobiotin

• CAT Number: I044718
• CAS Number: 1426828-06-9
• Molecular Formula: C18H34N6O5
• Molecular Weight: 414.50
• Purity: ≥95%
• Synonyms: N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide
• IUPAC Name: N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-6-(5-methyl-2-oxoimidazolidin-4-yl)hexanamide
• InChI: InChI=1S/C18H34N6O5/c1-15-16(23-18(26)22-15)5-3-2-4-6-17(25)20-7-9-27-11-13-29-14-12-28-10-8-21-24-19/h15-16H,2-14H2,1H3,(H,20,25)(H2,22,23,26)
• InChIKey: JIQVKRRASYKCEL-UHFFFAOYSA-N
• SMILES: CC1C(NC(=O)N1)CCCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-]

Azide-PEG3-Desthiobiotin（Cat No.:I044718）is a versatile bioconjugation reagent designed for reversible affinity purification and labeling applications. It features a desthiobiotin moiety, which binds specifically yet reversibly to streptavidin or avidin, allowing for gentle elution without harsh conditions. The PEG3 spacer enhances water solubility and reduces steric hindrance, improving biomolecule accessibility and reducing nonspecific interactions. The terminal azide group enables copper-catalyzed click chemistry (CuAAC) with alkyne-containing molecules. This reagent is widely used in proteomics, diagnostics, and targeted delivery applications where reversible binding and site-specific conjugation are critical for experimental flexibility and precision.