For research use only. Not for therapeutic Use.
AZD1656（Cat No.:I003522）is an orally bioavailable small-molecule glucokinase activator (GKA) developed for the treatment of type 2 diabetes mellitus. By enhancing glucokinase activity in pancreatic β-cells and hepatocytes, AZD1656 promotes glucose-stimulated insulin secretion and improves hepatic glucose utilization, thereby reducing hyperglycemia. Its dual action on insulin release and glucose metabolism makes it a promising therapeutic candidate for glycemic control. Beyond diabetes, AZD1656 has also been explored for potential benefits in immune modulation. It remains a valuable tool in metabolic and endocrinology research for novel antidiabetic strategies.
| CAS Number | 919783-22-5 |
| Synonyms | 3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide |
| Molecular Formula | C24H26N6O5 |
| Purity | ≥95% |
| IUPAC Name | 3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide |
| InChI | InChI=1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(H,27,29,31)/t16-/m0/s1 |
| InChIKey | FJEJHJINOKKDCW-INIZCTEOSA-N |
| SMILES | CC1=CN=C(C=N1)NC(=O)C2=CC(=CC(=C2)O[C@@H](C)COC)OC3=NC=C(N=C3)C(=O)N4CCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
