AZD-CO-Ph-PEG4-Ph-CO-AZD

• CAT Number: I045236
• CAS Number: 2569143-72-0
• Molecular Formula: C26H28N2O8
• Molecular Weight: 496.51
• Purity: ≥95%
• Synonyms: 1-[4-[2-[2-[2-[4-(2-oxoazetidine-1-carbonyl)phenoxy]ethoxy]ethoxy]ethoxy]benzoyl]azetidin-2-one
• InChI: InChI=1S/C26H28N2O8/c29-23-9-11-27(23)25(31)19-1-5-21(6-2-19)35-17-15-33-13-14-34-16-18-36-22-7-3-20(4-8-22)26(32)28-12-10-24(28)30/h1-8H,9-18H2
• InChIKey: UTXXKKZMYZBDCT-UHFFFAOYSA-N
• SMILES: C1CN(C1=O)C(=O)C2=CC=C(C=C2)OCCOCCOCCOC3=CC=C(C=C3)C(=O)N4CCC4=O

AZD-CO-Ph-PEG4-Ph-CO-AZD（Cat No.:I045236）is a symmetrical, bifunctional azide-containing crosslinker featuring two azidophenyl groups connected via a PEG4 spacer. The PEG4 linker enhances water solubility, flexibility, and reduces steric hindrance, facilitating efficient bioconjugation in click chemistry applications. The azide groups enable copper-catalyzed or strain-promoted azide–alkyne cycloaddition (CuAAC or SPAAC), allowing site-specific attachment to alkyne-functionalized molecules. This reagent is valuable for chemical biology, drug delivery, and materials science, enabling precise construction of multifunctional biomolecules, probes, and polymers. Its design supports applications requiring controlled molecular spacing and improved reaction efficiency in aqueous or mixed solvent systems.