For research use only. Not for therapeutic Use.
AZD 2066（Cat No.:I011256）is an investigational compound developed by AstraZeneca as a selective metabotropic glutamate receptor 5 (mGluR5) antagonist. By blocking mGluR5 signaling, AZD 2066 modulates glutamatergic neurotransmission, which is implicated in pain perception, anxiety, depression, and neurodegenerative disorders. Preclinical studies suggest it can reduce neuropathic pain and improve mood-related behaviors without the side effects typical of conventional therapies. As part of central nervous system research, AZD 2066 has been explored for conditions such as chronic pain, anxiety disorders, and cognitive dysfunction, highlighting its potential therapeutic applications.
| CAS Number | 934282-55-0 |
| Synonyms | 5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2-oxazole |
| Molecular Formula | C19H16ClN5O2 |
| Purity | ≥95% |
| IUPAC Name | 5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2-oxazole |
| InChI | InChI=1S/C19H16ClN5O2/c1-12(16-11-17(27-24-16)14-4-3-5-15(20)10-14)26-19-23-22-18(25(19)2)13-6-8-21-9-7-13/h3-12H,1-2H3/t12-/m1/s1 |
| InChIKey | SXWHYTICXCLKDG-GFCCVEGCSA-N |
| SMILES | C[C@H](C1=NOC(=C1)C2=CC(=CC=C2)Cl)OC3=NN=C(N3C)C4=CC=NC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
