For research use only. Not for therapeutic Use.
AZ506（Cat No.:I022806）is a selective small-molecule inhibitor of bromodomain-containing protein 4 (BRD4), a key epigenetic regulator involved in gene transcription. By targeting the bromodomain of BRD4, AZ506 disrupts its interaction with acetylated histones, leading to downregulation of oncogenes like MYC. This mechanism makes AZ506 a promising candidate for cancer therapy, particularly in malignancies driven by aberrant transcriptional activity. Preclinical studies have demonstrated its potential to suppress tumor growth and promote apoptosis. AZ506 provides a valuable tool for studying BET protein function and exploring targeted therapies in cancer epigenetics.
| CAS Number | 2043321-54-4 |
| Synonyms | 5-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]phenyl]-N-(3-pyrrolidin-1-ylpropyl)pyridine-3-carboxamide |
| Molecular Formula | C33H40N6O |
| Purity | ≥95% |
| IUPAC Name | 5-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]phenyl]-N-(3-pyrrolidin-1-ylpropyl)pyridine-3-carboxamide |
| InChI | InChI=1S/C33H40N6O/c40-33(35-13-7-16-37-14-5-6-15-37)28-22-27(23-34-24-28)30-9-2-4-11-32(30)39-20-18-38(19-21-39)17-12-26-25-36-31-10-3-1-8-29(26)31/h1-4,8-11,22-25,36H,5-7,12-21H2,(H,35,40) |
| InChIKey | VCPDGNYFXJYJFB-UHFFFAOYSA-N |
| SMILES | C1CCN(C1)CCCNC(=O)C2=CN=CC(=C2)C3=CC=CC=C3N4CCN(CC4)CCC5=CNC6=CC=CC=C65 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
