For research use only. Not for therapeutic Use.
AZ3976（Cat No.:I022803）is a selective and potent inhibitor of MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4), a kinase involved in inflammatory signaling, metabolic regulation, and cancer progression. By targeting MAP4K4, AZ3976 suppresses pro-inflammatory cytokine production and modulates insulin sensitivity, making it useful in research on metabolic disorders such as type 2 diabetes and obesity. Additionally, it shows promise in studies on tumorigenesis and cell migration. AZ3976 enables researchers to explore MAP4K4-mediated pathways, assess its therapeutic potential, and investigate its role in inflammation, cancer, and metabolic diseases.
| CAS Number | 1418747-15-5 |
| Synonyms | tert-butyl 3-[(4-oxo-3H-pyrido[2,3-d]pyrimidin-2-yl)amino]azetidine-1-carboxylate |
| Molecular Formula | C15H19N5O3 |
| Purity | ≥95% |
| IUPAC Name | tert-butyl 3-[(4-oxo-3H-pyrido[2,3-d]pyrimidin-2-yl)amino]azetidine-1-carboxylate |
| InChI | InChI=1S/C15H19N5O3/c1-15(2,3)23-14(22)20-7-9(8-20)17-13-18-11-10(12(21)19-13)5-4-6-16-11/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18,19,21) |
| InChIKey | CKUDSTVQYFRZJW-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)N1CC(C1)NC2=NC3=C(C=CC=N3)C(=O)N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
