For research use only. Not for therapeutic Use.
AZ3391（Cat No.:I044033）is a selective small-molecule inhibitor targeting diacylglycerol O-acyltransferase 1 (DGAT1), a key enzyme involved in triglyceride synthesis and lipid metabolism. By blocking DGAT1 activity, AZ3391 reduces triglyceride accumulation and modulates lipid absorption and energy homeostasis. It is particularly valuable in metabolic disease research, including obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). AZ3391 also helps explore gastrointestinal and lipid-related side effects linked to DGAT1 inhibition. Its specificity and oral bioavailability make it a useful tool for dissecting the therapeutic potential of DGAT1-targeted metabolic interventions.
| CAS Number | 2756333-42-1 |
| Synonyms | 5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N,6-dimethylpyridine-2-carboxamide |
| Molecular Formula | C23H27FN6O2 |
| Purity | ≥95% |
| IUPAC Name | 5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N,6-dimethylpyridine-2-carboxamide |
| InChI | InChI=1S/C23H27FN6O2/c1-4-16-23(32)28-21-17(27-16)6-5-15(20(21)24)13-29-9-11-30(12-10-29)19-8-7-18(22(31)25-3)26-14(19)2/h5-8H,4,9-13H2,1-3H3,(H,25,31)(H,28,32) |
| InChIKey | HLKLYCUPDHVKKZ-UHFFFAOYSA-N |
| SMILES | CCC1=NC2=C(C(=C(C=C2)CN3CCN(CC3)C4=C(N=C(C=C4)C(=O)NC)C)F)NC1=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
