For research use only. Not for therapeutic Use.
AZ10606120 dihydrochloride（Cat No.:I003355）is a selective and potent antagonist of the P2X7 receptor, an ATP-gated ion channel implicated in inflammation, immune regulation, and cell death pathways. By blocking P2X7 activation, it prevents pore formation, calcium influx, and subsequent release of pro-inflammatory cytokines such as IL-1β. This compound is widely used in studies of neuroinflammation, chronic pain, and autoimmune disease models, offering insight into P2X7-mediated signaling. AZ10606120 dihydrochloride is a valuable pharmacological tool for investigating therapeutic targets in inflammation and neurological disorders.
| CAS Number | 607378-18-7 |
| Synonyms | 2-(1-adamantyl)-N-[2-[2-(2-hydroxyethylamino)ethylamino]quinolin-5-yl]acetamide;dihydrochloride |
| Molecular Formula | C25H36Cl2N4O2 |
| Purity | ≥95% |
| IUPAC Name | 2-(1-adamantyl)-N-[2-[2-(2-hydroxyethylamino)ethylamino]quinolin-5-yl]acetamide;dihydrochloride |
| InChI | InChI=1S/C25H34N4O2.2ClH/c30-9-8-26-6-7-27-23-5-4-20-21(28-23)2-1-3-22(20)29-24(31)16-25-13-17-10-18(14-25)12-19(11-17)15-25;;/h1-5,17-19,26,30H,6-16H2,(H,27,28)(H,29,31);2*1H |
| InChIKey | BVFONFUUWORSPO-UHFFFAOYSA-N |
| SMILES | C1C2CC3CC1CC(C2)(C3)CC(=O)NC4=CC=CC5=C4C=CC(=N5)NCCNCCO.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
