For research use only. Not for therapeutic Use.
AZ-Dyrk1B-33（Cat No.:I011262）is a selective small-molecule inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1B (DYRK1B), an enzyme implicated in cancer cell survival, metabolism, and drug resistance. By blocking DYRK1B activity, AZ-Dyrk1B-33 disrupts tumor-promoting signaling pathways and sensitizes cancer cells to therapeutic interventions. Preclinical studies suggest its potential in targeting solid tumors and hematological malignancies where DYRK1B is overexpressed. As a chemical probe, it is valuable for elucidating DYRK1B’s role in oncogenesis and metabolic regulation, supporting drug discovery and mechanistic research in oncology and cell biology.
| CAS Number | 1679330-37-0 |
| Synonyms | 1-benzyl-3-(2-methylpyrimidin-4-yl)pyrrolo[2,3-c]pyridine |
| Molecular Formula | C19H16N4 |
| Purity | ≥95% |
| IUPAC Name | 1-benzyl-3-(2-methylpyrimidin-4-yl)pyrrolo[2,3-c]pyridine |
| InChI | InChI=1S/C19H16N4/c1-14-21-10-8-18(22-14)17-13-23(12-15-5-3-2-4-6-15)19-11-20-9-7-16(17)19/h2-11,13H,12H2,1H3 |
| InChIKey | CZCUSHJQJWKYTD-UHFFFAOYSA-N |
| SMILES | CC1=NC=CC(=N1)C2=CN(C3=C2C=CN=C3)CC4=CC=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
