AXC-715 trihydrochloride

• CAT Number: I044647
• CAS Number: 2479276-17-8
• Molecular Formula: C18H28Cl3N5
• Molecular Weight: 420.81
• Purity: ≥95%
• Synonyms: 1-(4-aminobutyl)-2-butylimidazo[4,5-c]quinolin-4-amine;trihydrochloride
• InChI: InChI=1S/C18H25N5.3ClH/c1-2-3-10-15-22-16-17(23(15)12-7-6-11-19)13-8-4-5-9-14(13)21-18(16)20;;;/h4-5,8-9H,2-3,6-7,10-12,19H2,1H3,(H2,20,21);3*1H
• InChIKey: ZSUHKPUPLPQJGC-UHFFFAOYSA-N
• SMILES: CCCCC1=NC2=C(N1CCCCN)C3=CC=CC=C3N=C2N.Cl.Cl.Cl

AXC-715 trihydrochloride（Cat No.:I044647）is a potent small-molecule dual agonist of Toll-like receptors 7 and 8 (TLR7/8), designed to activate innate immune responses. With a molecular formula of C₁₈H₂₈Cl₃N₅ and a molecular weight of 420.81 g/mol, it is commonly used in immuno-oncology to enhance tumor immunogenicity, often by conjugating to antibodies such as anti–PD-L1. AXC-715 promotes cytokine production and dendritic cell activation, making it valuable for vaccine adjuvant research and immune therapy development. Supplied as a highly pure trihydrochloride salt, it is soluble in DMSO and stable under appropriate storage conditions.