Atpenin A5（Cat No.:M028427）is a potent and selective inhibitor of mitochondrial complex II (succinate dehydrogenase), a key enzyme in both the tricarboxylic acid (TCA) cycle and the electron transport chain. By targeting complex II, Atpenin A5 disrupts cellular respiration and ATP production, leading to increased reactive oxygen species (ROS) and apoptosis in energy-dependent cells. It is widely used in studies of mitochondrial function, oxidative stress, and metabolic regulation. Atpenin A5 is also valuable in cancer and neurodegeneration research, where altered mitochondrial activity plays a critical role in disease progression.