For research use only. Not for therapeutic Use.
Atopaxar（Cat No.:I003179）is an oral thrombin receptor (PAR-1) antagonist developed for its antiplatelet and antithrombotic effects. By selectively inhibiting protease-activated receptor-1, Atopaxar blocks thrombin-induced platelet activation without affecting coagulation pathways, offering a potentially safer alternative to conventional antiplatelet drugs. It has been investigated for use in acute coronary syndrome and other cardiovascular conditions. Atopaxar is also valuable in research exploring thrombin signaling, platelet biology, and inflammation-related vascular events. Though clinical development was discontinued, it remains a useful tool in preclinical studies.
| CAS Number | 751475-53-3 |
| Synonyms | 1-(3-tert-butyl-4-methoxy-5-morpholin-4-ylphenyl)-2-(5,6-diethoxy-4-fluoro-3-imino-1H-isoindol-2-yl)ethanone |
| Molecular Formula | C29H38FN3O5 |
| Purity | ≥95% |
| IUPAC Name | 1-(3-tert-butyl-4-methoxy-5-morpholin-4-ylphenyl)-2-(5,6-diethoxy-4-fluoro-3-imino-1H-isoindol-2-yl)ethanone |
| InChI | InChI=1S/C29H38FN3O5/c1-7-37-23-15-19-16-33(28(31)24(19)25(30)27(23)38-8-2)17-22(34)18-13-20(29(3,4)5)26(35-6)21(14-18)32-9-11-36-12-10-32/h13-15,31H,7-12,16-17H2,1-6H3 |
| InChIKey | QWKAUGRRIXBIPO-UHFFFAOYSA-N |
| SMILES | CCOC1=C(C(=C2C(=C1)CN(C2=N)CC(=O)C3=CC(=C(C(=C3)N4CCOCC4)OC)C(C)(C)C)F)OCC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
