ATF3 inducer 1

• CAT Number: I042385
• Molecular Formula: C12H10N2O3
• Molecular Weight: 230.22
• Purity: ≥95%
• Synonyms: 7-methoxy-3-methyl-2H-chromeno[4,3-c]pyrazol-4-one
• InChI: InChI=1S/C12H10N2O3/c1-6-10-11(14-13-6)8-4-3-7(16-2)5-9(8)17-12(10)15/h3-5H,1-2H3,(H,13,14)
• InChIKey: XAKSOGPEDDVQGM-UHFFFAOYSA-N
• SMILES: CC1=C2C(=NN1)C3=C(C=C(C=C3)OC)OC2=O

ATF3 inducer 1 (Cat No.: I042385) is a small molecule compound that selectively upregulates the expression of Activating Transcription Factor 3 (ATF3), a key regulator of cellular stress responses, apoptosis, and immune modulation. By promoting ATF3 activity, this compound is valuable for investigating mechanisms of inflammation, cancer progression, and metabolic regulation. ATF3 inducer 1 serves as a useful tool in preclinical research for studying stress-related signaling pathways and holds potential for therapeutic exploration in diseases involving dysregulated stress and immune responses.

Reference

[1]. Chang YH, et al. Exploration and biological evaluation of 7-methoxy-3-methyl-1H-chromeno[4,3-c]pyrazol-4-one as an activating transcription factor 3 inducer for managing metabolic syndrome. Eur J Med Chem. 2022 Nov 25;246:114951.
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