AT791

• CAT Number: I022590
• CAS Number: 1219962-49-8
• Molecular Formula: C23H31N3O3
• Molecular Weight: 397.51
• Purity: ≥95%
• Synonyms: 3-[4-[6-[3-(dimethylamino)propoxy]-1,3-benzoxazol-2-yl]phenoxy]-N,N-dimethylpropan-1-amine
• InChI: InChI=1S/C23H31N3O3/c1-25(2)13-5-15-27-19-9-7-18(8-10-19)23-24-21-12-11-20(17-22(21)29-23)28-16-6-14-26(3)4/h7-12,17H,5-6,13-16H2,1-4H3
• InChIKey: JKFYWFWUJUHSMZ-UHFFFAOYSA-N
• SMILES: CN(C)CCCOC1=CC=C(C=C1)C2=NC3=C(O2)C=C(C=C3)OCCCN(C)C

AT791（Cat No.:I022590）is a small-molecule inhibitor targeting hepatitis B virus (HBV) core protein, designed to interfere with viral replication by disrupting capsid assembly. It belongs to the class of core protein allosteric modulators (CpAMs), which induce the formation of aberrant or empty capsids, thereby preventing proper viral packaging and genome replication. AT791 has shown potent antiviral activity in preclinical studies by reducing HBV DNA levels and impairing cccDNA replenishment. Its mechanism offers a novel therapeutic approach for chronic HBV infection, with potential to enhance current antiviral regimens and support functional cure strategies.