Asp-Asp-Asp-Asp-Asp-Asp

• CAT Number: M098991
• CAS Number: 145224-96-0
• Molecular Formula: C24H32N6O19
• Molecular Weight: 708.54
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]butanedioic acid
• InChI: InChI=1S/C24H32N6O19/c25-7(1-13(31)32)19(43)26-8(2-14(33)34)20(44)27-9(3-15(35)36)21(45)28-10(4-16(37)38)22(46)29-11(5-17(39)40)23(47)30-12(24(48)49)6-18(41)42/h7-12H,1-6,25H2,(H,26,43)(H,27,44)(H,28,45)(H,29,46)(H,30,47)(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,48,49)/t7-,8-,9-,10-,11-,12-/m0/s1
• InChIKey: AVTYRFNMUKCTIC-ZNSCXOEOSA-N
• SMILES: C(C(C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)O)N)C(=O)O

Asp-Asp-Asp-Asp-Asp-Asp (Cat No.: M098991) is a synthetic hexapeptide composed of six consecutive aspartic acid (Asp) residues. This polyanionic peptide exhibits strong negative charge at physiological pH, making it useful for studying electrostatic interactions, calcium binding, and mineralization processes such as bone formation. It is often used in biomaterials research, especially for functionalizing surfaces to promote hydroxyapatite deposition. Due to its acidic nature, this peptide can also serve as a model for understanding protein folding, aggregation, and the behavior of acidic domains in proteins.

Reference

[1]. Colman PM, et al. Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature. 1983 May 5-11;303(5912):41-4.
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