AS-85

• CAT Number: I045287
• CAS Number: 2323623-80-7
• Molecular Formula: C26H28F3N5O3S2
• Molecular Weight: 579.66
• Purity: ≥95%
• Synonyms: N-[[3-(3-carbamothioylphenyl)-1-[1-(trifluoromethylsulfonyl)piperidin-4-yl]indol-6-yl]methyl]azetidine-3-carboxamide
• InChI: InChI=1S/C26H28F3N5O3S2/c27-26(28,29)39(36,37)33-8-6-20(7-9-33)34-15-22(17-2-1-3-18(11-17)24(30)38)21-5-4-16(10-23(21)34)12-32-25(35)19-13-31-14-19/h1-5,10-11,15,19-20,31H,6-9,12-14H2,(H2,30,38)(H,32,35)
• InChIKey: WDQKQCWRQIVDBA-UHFFFAOYSA-N
• SMILES: C1CN(CCC1N2C=C(C3=C2C=C(C=C3)CNC(=O)C4CNC4)C5=CC(=CC=C5)C(=S)N)S(=O)(=O)C(F)(F)F

AS-85（Cat No.:I045287）is a synthetic small-molecule inhibitor designed to modulate inflammatory signaling pathways by targeting specific kinases involved in cytokine production and immune cell activation. Its mechanism of action focuses on suppressing pro-inflammatory mediators, making it valuable for research in autoimmune diseases, chronic inflammation, and related pathological conditions. Preclinical studies suggest AS-85 can reduce tissue damage and restore immune balance without broadly suppressing immune function. With favorable stability and selectivity, AS-85 serves as a promising tool for investigating targeted anti-inflammatory strategies and developing next-generation therapeutics for immune-mediated disorders.