Aristolochic acid C

• CAT Number: R050013
• CAS Number: 4849-90-5
• Molecular Formula: C16H9NO7
• Molecular Weight: 327.25
• Purity: ≥95%
• Synonyms: 10-hydroxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
• InChI: InChI=1S/C16H9NO7/c18-8-2-1-7-3-11(17(21)22)13-10(16(19)20)5-12-15(24-6-23-12)14(13)9(7)4-8/h1-5,18H,6H2,(H,19,20)
• InChIKey: NBFGYDJKTHENDP-UHFFFAOYSA-N
• SMILES: C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O

Aristolochic acid C（Cat No.:R050013）is a nitrophenanthrene carboxylic acid derivative isolated from plants of the Aristolochia genus. Structurally, it shares the characteristic nitrophenanthrene core of aristolochic acids, responsible for both its bioactivity and toxicity. Aristolochic acid C exhibits antimicrobial and antitumor properties but is also highly nephrotoxic and carcinogenic, inducing DNA adduct formation that leads to kidney damage and urothelial cancer. Due to its severe toxicity, its medicinal use is prohibited, and current research focuses on understanding its toxicological mechanisms and biosynthetic pathways.