Aripiprazole monohydrate

• CAT Number: I022425
• CAS Number: 851220-85-4
• Molecular Formula: C23H29Cl2N3O3
• Molecular Weight: 466.4
• Purity: 99%
• Synonyms: Aripiprazole monohydrate; OPC 14597; OPC14597; OPC-14597; OPC 31; OPC-31; OPC31; Abilitat
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
• IUPAC Name: 7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one hydrate
• InChI: 1S/C23H27Cl2N3O2.H2O/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18;/h3-6,8,16H,1-2,7,9-15H2,(H,26,29);1H2
• InChIKey: UXQBDXJXIVDBTF-UHFFFAOYSA-N
• SMILES: ClC1=C(Cl)C(N2CCN(CCCCOC3=CC(NC(CC4)=O)=C4C=C3)CC2)=CC=C1.O

Aripiprazole monohydrate (Cat.No:I022425) is a medication used to treat mental or mood disorders, such as schizophrenia, bipolar disorder, or major depressive disorder. It works by changing the balance of certain natural substances in the brain.

Reference

1: Cameron C, Zummo J, Desai D, Drake C, Hutton B, Kotb A, Weiden PJ. Efficacy and safety of aripiprazole lauroxil once-monthly versus aripiprazole once-monthly long-acting injectable formulations in patients with acute symptoms of schizophrenia: an indirect comparison of two double-blind placebo-controlled studies. Curr Med Res Opin. 2018 Apr;34(4):725-733. doi: 10.1080/03007995.2017.1410471. Epub 2018 Jan 10. PubMed PMID: 29179595.
2: Salzman PM, Raoufinia A, Legacy S, Such P, Eramo A. Plasma concentrations and dosing of 2 long-acting injectable formulations of aripiprazole. Neuropsychiatr Dis Treat. 2017 Apr 20;13:1125-1129. doi: 10.2147/NDT.S133433. eCollection 2017. PubMed PMID: 28461748; PubMed Central PMCID: PMC5404798.