For research use only. Not for therapeutic Use.
Argifin（Cat No.:I015124）is a natural cyclic pentapeptide isolated from fungal sources, recognized as a potent chitinase inhibitor. By binding to the active site of chitinases, Argifin prevents the enzymatic degradation of chitin, a structural polysaccharide found in fungi, insects, and parasites. This makes it a valuable research tool for studying chitin metabolism and developing antifungal or antiparasitic strategies. Researchers employ Argifin in infection disease research, structural biology, and drug discovery to evaluate chitinase as a therapeutic target. Its specificity provides insight into carbohydrate–protein interactions and enzyme inhibition.
| CAS Number | 243975-37-3 |
| Synonyms | (2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid |
| Molecular Formula | C29H41N9O10 |
| Purity | ≥95% |
| IUPAC Name | (2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid |
| InChI | InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18+,19+,20+/m1/s1 |
| InChIKey | UHBHXSDKGLPPGO-HTDHLNIYSA-N |
| SMILES | C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@@H](CC(=O)N[C@@H](CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
