Arg-Gly-Asp-Cys TFA

• CAT Number: I044767
• CAS Number: 2171504-22-4
• Molecular Formula: C15H27N7O7S.xC2HF3O2
• Molecular Weight: 449.48 (free acid)
• Purity: ≥95%
• Synonyms: (3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid
• IUPAC Name: (3R)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C15H27N7O7S.C2HF3O2/c16-7(2-1-3-19-15(17)18)12(26)20-5-10(23)21-8(4-11(24)25)13(27)22-9(6-30)14(28)29;3-2(4,5)1(6)7/h7-9,30H,1-6,16H2,(H,20,26)(H,21,23)(H,22,27)(H,24,25)(H,28,29)(H4,17,18,19);(H,6,7)/t7-,8+,9-;/m0./s1
• InChIKey: AJFGGKXZCJCXNM-HBJOHWKNSA-N
• SMILES: C(C[C@@H](C(=O)NCC(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)O)N)CN=C(N)N.C(=O)(C(F)(F)F)O

Arg-Gly-Asp-Cys TFA（Cat No.:I044767）is a synthetic tetrapeptide featuring the RGD motif (Arg-Gly-Asp), known for its strong affinity to integrin receptors, especially those involved in cell adhesion and signaling. The terminal cysteine (Cys) allows site-specific conjugation to biomaterials or imaging agents via thiol chemistry. Supplied as a trifluoroacetate (TFA) salt for improved stability, this peptide is widely used in tissue engineering, drug delivery, and cancer research to study cell-matrix interactions. Its specificity to integrins makes it valuable for targeting tumor cells or promoting cell attachment in biomaterial design.