Arachidonyl-2-chloroethylamide

• CAT Number: R052776
• CAS Number: 220556-69-4
• Molecular Formula: C22H36ClNO
• Molecular Weight: 365.98
• Purity: ≥95%
• Synonyms: (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenamide; ACEA
• Storage: -80°C
• IUPAC Name: (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide
• InChI: InChI=1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
• InChIKey: vQNMGLLFMPXVFN-GOSISDBHSA-N
• SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCCl

Arachidonyl-2-chloroethylamide (Cat No.: R052776) is a synthetic cannabinoid analog and selective agonist of the CB1 receptor, structurally derived from arachidonic acid. It features an amide linkage between the arachidonyl chain and a 2-chloroethylamine group, enhancing its affinity and specificity for the endocannabinoid system. ACEA is widely used in pharmacological research to study CB1-mediated signaling pathways, neuroprotection, pain modulation, and appetite regulation. Its stability and receptor selectivity make it a valuable tool for exploring the therapeutic potential of cannabinoid receptor agonists.