For research use only. Not for therapeutic Use.
AR7 (Cat No.:I002682) is a retinoic acid receptor alpha (RARα) antagonist. Ar7 is a CMA booster for biological studies of retinoic acid derivative-mediated chemical regulation of autophagy in chaperone cells. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| CAS Number | 80306-38-3 |
| Synonyms | AR-7; AR 7; AR7; Atypical retinoid 7.;7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine |
| Molecular Formula | C15H12ClNO |
| Purity | ≥95% |
| Target | Vitamin D Related/Nuclear Receptor |
| Solubility | Soluble in DMSO |
| Storage | Sealed in dry,2-8°C |
| IUPAC Name | 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine |
| InChI | InChI=1S/C15H12ClNO/c1-10-2-4-11(5-3-10)14-9-18-15-8-12(16)6-7-13(15)17-14/h2-8H,9H2,1H3 |
| InChIKey | MVOZLTFXYGHZPM-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2 |
| Reference | </br>1:Physiological adaptations and tolerance towards higher concentration of selenite (Se(+4)) in Enterobacter sp. AR-4, Bacillus sp. AR-6 and Delftia tsuruhatensis AR-7. Prakash D, Pandey J, Tiwary BN, Jain RK.Extremophiles. 2010 May;14(3):261-72. doi: 10.1007/s00792-010-0305-8. Epub 2010 Mar 16. PMID: 20232096 </br>2:Natural and experimental Salmonella arizonae 18:z4,z32 (Ar. 7:1,7,8) infection in broilers. Bacteriological and histopathological survey of eye and brain lesions. Silva EN, Hipolito O, Grecchi R.Avian Dis. 1980 Jul-Sep;24(3):631-6. PMID: 7447834 |
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