APS6-45（Cat No.:I022346）is a synthetic compound identified as a selective inhibitor of the deubiquitinating enzyme USP7 (ubiquitin-specific protease 7), which plays a crucial role in regulating protein stability, especially in the p53-MDM2 signaling pathway. By inhibiting USP7, APS6-45 leads to the stabilization of tumor suppressor proteins like p53, promoting apoptosis in cancer cells. Its targeted mechanism offers a promising therapeutic strategy for cancers where USP7 is overactive. APS6-45 has demonstrated potent anti-proliferative activity in preclinical models, making it a valuable tool for studying ubiquitin-mediated signaling and cancer therapeutics.