Aprinocarsen sodium

• CAT Number: I042484
• CAS Number: 331257-53-5
• Molecular Formula: C196H230N68Na19O105P19S19
• Molecular Weight: 6852.85
• Purity: ≥95%

Aprinocarsen sodium (Cat No.: I042484) is the sodium salt form of aprinocarsen, an antisense oligonucleotide designed to inhibit the production of protein kinase C-alpha (PKC-α), a key enzyme involved in cell proliferation, survival, and drug resistance in cancer. By binding to PKC-α mRNA, it blocks translation, thereby reducing tumor growth and enhancing the effectiveness of chemotherapeutic agents. Aprinocarsen sodium has been evaluated in clinical trials for various cancers, including lung and prostate, offering a targeted approach to disrupt oncogenic signaling pathways at the genetic level.

Reference

[1]. https://pubmed.ncbi.nlm.nih.gov/8758918/