For research use only. Not for therapeutic Use.
Aplaviroc hydrochloride（Cat No.:I002593）is a selective antagonist of the CCR5 (C-C chemokine receptor type 5), a receptor involved in immune cell trafficking and a key co-receptor for HIV-1 entry into host cells. By blocking CCR5, Aplaviroc prevents HIV from binding and entering T cells, making it a valuable antiviral research tool. It has also been investigated for potential roles in modulating inflammation and autoimmune diseases. The hydrochloride salt form improves its solubility and stability. Aplaviroc hydrochloride is intended for laboratory research use only; not for clinical or therapeutic applications in humans or animals.
| CAS Number | 461023-63-2 |
| Synonyms | 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride |
| Molecular Formula | C33H44ClN3O6 |
| Purity | ≥95% |
| IUPAC Name | 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride |
| InChI | InChI=1S/C33H43N3O6.ClH/c1-2-3-19-36-30(38)28(29(37)24-7-5-4-6-8-24)34-32(41)33(36)17-20-35(21-18-33)22-23-9-13-26(14-10-23)42-27-15-11-25(12-16-27)31(39)40;/h9-16,24,28-29,37H,2-8,17-22H2,1H3,(H,34,41)(H,39,40);1H/t28-,29-;/m1./s1 |
| InChIKey | QNNBMSGFNQRUEH-PQQSRXGVSA-N |
| SMILES | CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCCCC5)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
