AP1867

• CAT Number: I019585
• CAS Number: 195514-23-9
• Molecular Formula: C₃₈H₄₇NO₁₁
• Molecular Weight: 693.78
• Purity: ≥95%
• IUPAC Name: 2-[3-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid
• InChI: InChI=1S/C38H47NO11/c1-7-28(26-21-33(46-4)36(48-6)34(22-26)47-5)37(42)39-18-9-8-13-29(39)38(43)50-30(25-11-10-12-27(20-25)49-23-35(40)41)16-14-24-15-17-31(44-2)32(19-24)45-3/h10-12,15,17,19-22,28-30H,7-9,13-14,16,18,23H2,1-6H3,(H,40,41)/t28-,29-,30+/m0/s1
• InChIKey: XCCRAOPQCACRFC-OIFRRMEBSA-N
• SMILES: CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)O

AP1867 (Cat.No:I019585) is a chemical compound that is widely used in research to control protein function in cells. It is a synthetic ligand that can selectively bind to a modified protein, allowing for the induction or inhibition of the protein’s activity. AP1867 has shown promise in cancer research and other biomedical applications. Its CAS number is 195514-23-9.

Reference

[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.