AP1867 (Cat.No:I019585) is a chemical compound that is widely used in research to control protein function in cells. It is a synthetic ligand that can selectively bind to a modified protein, allowing for the induction or inhibition of the protein’s activity. AP1867 has shown promise in cancer research and other biomedical applications. Its CAS number is 195514-23-9.
| Catalog Number | I019585 |
| CAS Number | 195514-23-9 |
| Molecular Formula | C₃₈H₄₇NO₁₁ |
| Purity | 95% |
| IUPAC Name | 2-[3-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid |
| InChI | InChI=1S/C38H47NO11/c1-7-28(26-21-33(46-4)36(48-6)34(22-26)47-5)37(42)39-18-9-8-13-29(39)38(43)50-30(25-11-10-12-27(20-25)49-23-35(40)41)16-14-24-15-17-31(44-2)32(19-24)45-3/h10-12,15,17,19-22,28-30H,7-9,13-14,16,18,23H2,1-6H3,(H,40,41)/t28-,29-,30+/m0/s1 |
| InChIKey | XCCRAOPQCACRFC-OIFRRMEBSA-N |
| SMILES | CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)O |
| Reference | [1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441. |
