Antitrypanosomal agent 9

• CAT Number: I042522
• CAS Number: 438474-67-0
• Molecular Formula: C22H27NO3
• Molecular Weight: 353.45
• Purity: ≥95%
• Synonyms: [4-[(4-ethoxyphenoxy)methyl]phenyl]-(3-methylpiperidin-1-yl)methanone
• InChI: InChI=1S/C22H27NO3/c1-3-25-20-10-12-21(13-11-20)26-16-18-6-8-19(9-7-18)22(24)23-14-4-5-17(2)15-23/h6-13,17H,3-5,14-16H2,1-2H3
• InChIKey: WFMWFIJMQIVRKV-UHFFFAOYSA-N
• SMILES: CCOC1=CC=C(C=C1)OCC2=CC=C(C=C2)C(=O)N3CCCC(C3)C

Antitrypanosomal agent 9 (Cat No.: I042522) is an experimental compound developed to combat Trypanosoma species, the protozoan parasites responsible for diseases such as African sleeping sickness and Chagas disease. This agent targets vital parasite-specific pathways, such as energy metabolism, DNA replication, or surface protein synthesis, leading to parasite death while minimizing host toxicity. Antitrypanosomal agent 9 is being evaluated in preclinical studies for its efficacy, selectivity, and pharmacokinetic profile, offering potential as a next-generation treatment option for neglected tropical diseases caused by trypanosome infections.

Reference

[1]. Manos-Turvey Alexandra, et al. Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. Med Chem Commun. 2015, 6(3), 403–406.