Anisatin

• CAT Number: I044961
• CAS Number: 5230-87-5
• Molecular Formula: C15H20O8
• Molecular Weight: 328.31
• Purity: ≥95%
• Synonyms: (1S,2R,4R,5R,6S,7R,8R,11R)-4,5,7,11-tetrahydroxy-2,7-dimethylspiro[9-oxatricyclo[6.3.1.01,5]dodecane-6,3′-oxetane]-2′,10-dione
• IUPAC Name: (1S,2R,4R,5R,6S,7R,8R,11R)-4,5,7,11-tetrahydroxy-2,7-dimethylspiro[9-oxatricyclo[6.3.1.01,5]dodecane-6,3'-oxetane]-2',10-dione
• InChI: InChI=1S/C15H20O8/c1-6-3-7(16)15(21)13(6)4-8(23-10(18)9(13)17)12(2,20)14(15)5-22-11(14)19/h6-9,16-17,20-21H,3-5H2,1-2H3/t6-,7-,8-,9+,12+,13+,14+,15-/m1/s1
• InChIKey: GEVWHIDSUOMVRI-QWNPAUMXSA-N
• SMILES: C[C@@H]1C[C@H]([C@]2([C@@]13C[C@H]([C@]([C@@]24COC4=O)(C)O)OC(=O)[C@@H]3O)O)O

Anisatin（Cat No.:I044961）is a highly toxic sesquiterpene lactone isolated from plants of the Illicium genus, particularly Illicium anisatum (Japanese star anise). It is known for its potent neurotoxic and convulsant properties, acting as a non-competitive antagonist of the GABAA_AA​ receptor, thereby disrupting inhibitory neurotransmission in the central nervous system. Ingestion can lead to severe symptoms including seizures, vomiting, and neurotoxicity. Due to its toxicity, anisatin is of concern in food safety and toxicology. Despite its danger, it is studied for its molecular interactions in neuropharmacology and poison control research.