Ani9（Cat No.:I011371）is a potent and selective small-molecule inhibitor of the calcium-activated chloride channel ANO1 (TMEM16A), which plays key roles in epithelial secretion, smooth muscle contraction, and sensory processing. Unlike earlier inhibitors, Ani9 exhibits high specificity for ANO1 without significantly affecting related channels like ANO2 or CFTR. It is widely used in preclinical research to investigate ANO1’s involvement in disorders such as asthma, cystic fibrosis, and cancer. By selectively blocking ANO1 activity, Ani9 enables detailed studies of chloride channel physiology and supports the development of targeted therapeutic strategies.