Amylin, amide, human TFA

• CAT Number: I046001
• Molecular Formula: C167H262F3N51O57S2
• Molecular Weight: 4017.30
• Purity: ≥95%

Amylin, amide, human TFA(CAT: I046001) is a 37–amino acid peptide hormone co-secreted with insulin by pancreatic β-cells. It plays a critical role in glucose homeostasis by slowing gastric emptying, suppressing postprandial glucagon secretion, and promoting satiety. In research, synthetic human amylin is used to investigate diabetes, metabolic regulation, and neurodegenerative processes, as misfolded amylin aggregates are implicated in β-cell dysfunction and islet amyloidosis in type 2 diabetes. Amylin also shares structural similarities with calcitonin gene-related peptide (CGRP), linking it to studies in pain and neurobiology. This TFA salt form provides a reliable tool for endocrine and metabolic disease research.

Reference

[1]. Sisnande T, et al. Monoconjugation of Human Amylin with Methylpolyethyleneglycol. PLoS One. 2015 Oct 8;10(10):e0138803.
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