AMP-PCP disodium

• CAT Number: I015441
• CAS Number: 7414-56-4
• Molecular Formula: C11H16N5Na2O12P3
• Molecular Weight: 549.17
• Purity: ≥95%
• Synonyms: disodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-[[hydroxy(oxido)phosphoryl]methyl]phosphinate
• IUPAC Name: sodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl-hydroxyphosphinate
• InChI: InChI=1S/C11H18N5O12P3.Na/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-31(24,25)28-30(22,23)4-29(19,20)21;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21);/q;+1/p-1/t5-,7-,8-,11-;/m1./s1
• InChIKey: MKVIBVOIFQAVOC-YCSZXMBFSA-M
• SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(CP(=O)(O)[O-])O)O)O)N.[Na+]

AMP-PCP disodium（Cat No.:I015441）is a stable, non-hydrolyzable analog of adenosine monophosphate in which the oxygen of the phosphate chain is replaced by a methylene group, preventing enzymatic cleavage. Supplied as the disodium salt, it improves solubility for biochemical and cellular assays. Widely used in nucleotide-binding studies, AMP-PCP serves as a tool to investigate ATP- and AMP-dependent enzymes, including kinases, ATPases, and motor proteins. By mimicking natural nucleotides while resisting degradation, it helps researchers dissect energy metabolism, signal transduction, and structural dynamics in diverse biological processes.